ANA 12 Plus Profile (RDL)*

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Turnaround Time: 10-12 days
CPT Code:


Test Type: Serum 5 mL


Use: The ANA 12 Plus Profile is a reflexive assay. If the ANA titer is negative, no further tests are performed except for Anti-Ro Ab. Anti-Ro is performed to find the very small percentage of false negative ANAs. If the ANA titer is positive, the complete profile is performed. The ANA test detects autoantibodies that bind to the nuclear components of HEp-2 cells. A positive ANA titer is not specific but indicates the presence of one or more autoantibodies. Profiles of specific autoantibodies have diagnostic and potential prognostic utility.


Collection Details:

Collection Instructions:

Specimen: Serum

Volume: 5 mL

Minimum Volume: 4 mL (Note: This volume does not allow for repeat testing.)

Container: Red-top tube or gel-barrier tube

Collection: Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.

Storage Instructions: Refrigerate.