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Bone/Joint Bone Health

Bone/Joint



Bone-specific Alkaline Phosphatase (BAP)

Quantitative measurement of skeletal alkaline phosphatase to be used as an aid in the management of patients with Paget disease and osteoporosis.Serum specimens with significant elevations of liver alkaline phosphatase may cause aberrantly elevated results with the Ostase...

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C-Telopeptide (Collagen Cross-linked C-Telopeptide)

For in vitro diagnostic use as an indicator of human bone resorption. This test may be used as an aid in monitoring bone resorption changes of antiresorptive therapies in postmenopausal women, individuals with osteopenia, and in predicting skeletal response (bone mineral de...

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Deoxypyridinoline (Dpd) Cross-links (Serial Monitor)

The Dpd test can be used as a tool to assess bone resorption rates in healthy individuals and in patients with enhanced risk of developing metabolic bone disease. Significantly high levels of Dpd are found in children, in postmenopausal women due to estrogen deficiency, and...

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Intact N-Terminal Propeptide of Type 1 Procollagen

Indicator of type I collagen turnover.Results of this assay should be used in conjunction with pertinent clinical information for making diagnostic and therapeutic decisions. This assay is not recommended for use as a screening procedure to detect the presence of osteoporosis i...

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N-Telopeptide Cross-links (NTx), Urine

Evaluation of osteoporosis and assessment of antiresorptive therapy.Approximately 90% of the organic matrix of mammalian bone consists of type I collagen that is cross-linked at the N-terminal and C-terminal ends.1 This highly cross-linked structure provides for the basic fabric...

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Osteocalcin

Evaluate bone disease. Increased levels of osteocalcin are found in bone diseases characterized by increased bone turnover. Osteocalcin has been found to be elevated in Paget disease of the bone, cancer accompanied by bone metastases, primary hyperparathyroidism and renal osteody...

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Vitamin D, 25-Hydroxy

Rule out vitamin D deficiency.Values of vitamin D vary with exposure to sunlight. The assay measures other vitamin D metabolites, including dihydroxylated metabolites such as 24,25, 25,26, and 1,25 dihydroxy vitamin D; however, since the physiological concentrations of these meta...

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