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Bone/Joint Osteomalacia/Osteoporosis

Bone/Joint



N-Telopeptide Cross-links (NTx), Urine

Evaluation of osteoporosis and assessment of antiresorptive therapy.Approximately 90% of the organic matrix of mammalian bone consists of type I collagen that is cross-linked at the N-terminal and C-terminal ends.1 This highly cross-linked structure provides for the basic fabric...

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Phosphorus, 24-Hour Urine

Evaluate calcium/phosphorus balance.High urinary phosphorus (ie, increased renal losses) occurs in primary hyperparathyroidism, vitamin D deficiency, renal tubular acidosis, diuretic use. Phosphates are among the substances which may be lost in the Fanconi syndrome. Renal loss of...

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Vitamin D, 25-Hydroxy

Rule out vitamin D deficiency.Values of vitamin D vary with exposure to sunlight. The assay measures other vitamin D metabolites, including dihydroxylated metabolites such as 24,25, 25,26, and 1,25 dihydroxy vitamin D; however, since the physiological concentrations of these meta...

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