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Abacavir Hypersensitivity

Abacavir sulfate is a nucleoside reverse transcriptase inhibitor that is prescribed in combination with other antiviral drugs to treat HIV infection. In some patients, its use can cause abacavir sulfate hypersensitivity reaction (ABC HSR), a serious and sometimes fatal condition...

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Addison's Disease

Addison’s disease is a disease of the adrenal cortex caused by autoimmune destruction of the adrenal gland with fibrosis and mononuclear cell infiltration. Symptoms become evident when more than 90% of the adrenal gland is destroyed. Addison’s disease is characterized...

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Allopurinol Hypersensitivity

Allopurinol is the most commonly prescribed drug to treat gout, a disease characterized by the buildup of uric acid crystals in certain body tissues, as well as hyperuricemia.  It inhibits the action of a key enzyme involved in uric acid formation, xanthine oxidase.  Ho...

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Ankylosing Spondylitis

Ankylosing Spondylitis (AS) is one of the major forms of chronic inflammatory arthritis and is the prototypical example of the spondyloarthropathies, a group of chronic autoimmune joint diseases.Ankylosing Spondylitis has a global distribution, though rarer in Africans. It is c...

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APOE

The ApoE gene provides instructions for making a protein called apolipoprotein E. In the brain, ApoE is involved in clearing harmful plaques that form around nerve cells. These plaques are a hallmark of Alzheimer’s disease and consist of damaged proteins called amyloid &bet...

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Behcet's Disease

Behçet’s disease is a systemic inflammatory vasculitis, characterized by a course of remission and relapse of oral ulcers, genital ulcers, skin lesions and ocular lesions. It can affect the arteries and veins of almost any system and has been shown to involve th...

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Birdshot Chorioretinopathy

Birdshot Chorioretinopathy is a rare form of bilateral posterior uveitis, accounting for between 1 – 3% of all uveitis cases. A slight female predominance has been reported. The disease is uncommon in children.Birdshot Chorioretinopathy causes severe, progressive inflamma...

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Carbamazepine Hypersensitivity

Carbamazepine is an aromatic antiepileptic drug that has been approved for treatment of epilepsy and trigeminal neuralgia.  In approximately five to ten percent of patients, carbamazepine treatment is associated with carbamazepine-induced hypersensitivity reactions, which ar...

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Cardiac Health

The Kashi Cardiac Health Panel gives insight into how a patient’s genetic predisposition to cardiac problems can help healthcare providers optimize diagnosis and treatment. Cardiovascular disease is a leading contributor to morbidity and mortality, with over 17 million deat...

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