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Adrenal Adrenal Health


11-Deoxycortisol, LC/MS-MS (500171)

Evaluate hypothalamic-pituitary-adrenal axis and pituitary ACTH reserve. 11-Deoxycortisol is the immediate precursor of cortisol and follows the same catabolic pathways as cortisol.A primary use of 11-desoxycortisol testing is to detect congenital adrenal hyperplasia due...

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17-Hydroxypregnenolone, LC/MS-MS

In humans, the adrenal glands and the gonads produce steroid hormones.1,2 The formation of pregnenolone from cholesterol is the first step in steroidogenesis. Steroidogenesis continues along two paths from pregnenolone. 17-Hydroxypregnenolone is produced from pregnenolone t...

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21-Hydroxylase Antibodies

Addison's disease (chronic primary adrenal insufficiency) is commonly caused by autoimmune destruction of the adrenal cortex and is characterized by the presence of adrenal cortex autoantibodies in the serum. It can occur sporadically or in combination with other autoimmune...

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Addison's Disease

Addison's disease is a disease of the adrenal cortex caused by autoimmune destruction of the adrenal gland with fibrosis and mononuclear cell infiltration. Symptoms become evident when more than 90% of the adrenal gland is destroyed. Addison’s disease is characterized...

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Adrenal Function Panel (H)

This profile provides a comprehensive view of adrenal function and includes 4 cortisol levels timed throughout the day as well as DHEA. Symptoms that would indicate ordering this profile include:FatigueNervousnessWeaknessSugar cravingsInsomniaDizzy spellsHeadaches...

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Androsterone is a major metabolite of testosterone and androstenedione along with the enantiomer etiocholanolone. Androsterone is also part of the "backdoor pathway" from allopregnanolone to dihydrotestosterone, which has importance in certain disease states. Androsterone is one...

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Antiadrenal Antibodies (Adrenal Antibodies), Quantitative

Evaluate for adrenal insufficiency and Addison disease. Serum antibodies to adrenal cortical cells, usually of all three zones, are seen in 60% of patients with idiopathic Addison disease. They are present in only 5% to 17% of patients with tuberculous, fungal, or metastati...

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Catecholamines, Fractionated, Plasma

Diagnose pheochromocytoma and those paragangliomas which may secrete epinephrine, norepinephrine, or both. Such tumors may cause paroxysmal or persistent hypertension. Investigation of hypertensive patients, especially younger individuals, particularly when hypertension is...

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