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Immune System Immune Dysfunction

Immune System



Complement C3

Quantitation of C3 is used to detect individuals with inborn deficiency of this factor or those with immunologic disease in whom complement is consumed at an increased rate. These include lupus erythematosus, chronic active hepatitis, certain chronic infections, poststreptococcal...

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Complement C4

Quantitation of C4 is used to detect individuals with inborn deficiency of this factor or those with immunologic disease in whom hypercatabolism of complement causes reduced levels. These diseases include lupus erythematosus, serum sickness, certain glomerulonephritides, chro...

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Helper T-Lymphocyte Marker CD4

Monitor patient's helper/inducer T-cell status.HIV-1 infection results in a decrease of CD4 T cells, an increase of CD8 T cells, a decrease in the CD4:CD8 ratio, and a progressive destruction of immune function. In HIV-1 seropositive patients, enumeration of CD4 T cells may be...

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Immunofixation (IFE) and Protein Electrophoresis, Random Urine

Characterize the species of protein or proteins in cases of proteinuria. Techniques can identify albumin, γ-globulin, γ-globulin fragments (light chains, Bence Jones proteins); of value in the study of monoclonal gammopathies, lymphoproliferative diseases, including l...

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Interleukin-02 (IL-2), Plasma

Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen-activated T lymphocytes.1 IL-2 plays a role in promoting the clonal expansion of antigen-specific cytotoxic and suppressor T cells. In vitro studies suggest that IL-2 may also be produc...

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Interleukin-02 (IL-2), Serum

Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen- activated T lymphocytes.1 IL-2 plays a role in promoting the clonal expansion of antigen-specific cytotoxic and suppressor T cells. In vitro studies suggest that IL-2 may also be produ...

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Interleukin-02 Soluble Receptor a

Interleukin 2 (IL-2) is a pleiotropic cytokine produced primarily by mitogen- or antigen- activated T lymphocytes.1 IL-2 plays a role in promoting the clonal expansion of antigen-specific cytotoxic and suppressor T cells. In vitro studies suggest that IL-2 may also be produ...

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Interleukin-04 (IL-4), Serum

Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T lymphocytes, CD3+ cells, NK-T cells, mast cells, eosinophils, and basophils.1 IL-4 has multiple immune response modulation functions on a variety of cell types. It is an important regulator of isotype sw...

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Interleukin-08 (IL-8), Serum

Interleukin-8 (IL-8), a member if the neutrophil-specific CXC subfamily of chemokines, is a potent neutrophil chemotactic and activating factor.1 It is a primary inflammatory cytokine produced by many cells (including monocytes/macrophages, T cells, neutrophils, fibroblasts...

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