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Turnaround Time: 7 days
Test Type: Kit-Based, Stool


Zonulin is a protein secreted by intestinal cells that regulates intercellular tight junctions. Zonulin regulates barrier permeability. Serum zonulin correlates with intestinal permeability and lactulose/mannitol tests for intestinal permeability. High serum zonulin has been associated with celiac disease, type 1 diabetes, insulin resistance and type 2 diabetes, cancers, neurological conditions, and autoimmune diseases. The level of the zonulin antigen in stool may provide a noninvasive indication of intestinal permeability (“leaky gut”). 


Performing Lab: DSL

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