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Register NowApolipoprotein B
Create a Free Account to View PricesTurnaround Time: 1 - 2 days
CPT Code:
82172
Test Type: 2 mL Serum (preferred) or plasma
Stability Time:
|
Temperature |
Period |
|---|---|
|
Room temperature |
14 days |
|
Refrigerated |
14 days |
|
Frozen |
14 days |
|
Freeze/thaw cycles |
Stable x3 |
Reference Range:
|
Apolipoprotein B (mg/dL) |
|||
|---|---|---|---|
|
Desirable |
Borderline High |
High |
Very High |
|
<90 |
90 – 99 |
100 – 130 |
>130 |
|
ASCVD Risk Category |
Therapeutic Target APO B (mg/dL) |
|---|---|
|
Very High Risk |
<80 (if extreme risk <70) |
|
High Risk |
<90 |
|
Moderate Risk |
<90 |
Overview:
LDL and its major protein, apolipoprotein B, play an essential role in lipid transport and metabolism. Apo B may regulate cholesterol synthesis through its interaction with specific cell membrane receptors and by inhibition of HMG Co A reductase. This enzyme has been identified as the rate controlling enzyme in cholesterol biosynthesis. Apo B may be important in the genesis of atherosclerosis and its quantitation useful in the evaluation of patients at risk for or having coronary atherosclerosis (CAD). High levels indicate increased risk for CAD.
Colantonio DA, Kyriakopoulou L, Chan MK, et al. Closing the gaps in pediatric laboratory reference intervals: A CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children. Clin Chem. 2012 May; 58(5):854-868. PubMed 22371482
Contois JH, McConnell JP, Sethi AA, et al. Apolipoprotein B and cardiovascular disease risk: position statement from the AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices. Clin Chem. 2009 Mar;55(3):407-419. PubMed 19168552
Jacobson TA, Ito MK, Maki KC, et al. National lipid association recommendations for patient-centered management of dyslipidemia: part 1–full report. J Clin Lipidol. 2015 Mar-Apr;9(2):129-169. PubMed 25911072
Collection Details:
Patient Preparation:
Patient must be fasting 12 to 14 hours.
Collection Instructions:
Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Separate serum or plasma from cells. Transfer specimen to a plastic transport tube.
Maintain specimen at room temperature.