Boston Heart HDL Map (Particles Only) (809)

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CPT Code:


Test Type: 1.0 mL EDTA plasma Kit Based
Stability Time:

Refrigerated: 2 days (sample must be received within 2 days of collection)

Reference Range:


  Optimal Borderline Increased Risk
α-1 >35.0 25.0-35.0 <25.0
α-2 >55.0 45.0-55.0 <45.0
α-3 <20.0 20.0-25.0 >25.0
α-4 <20.0 20.0-25.0 >25.0
Preβ-1 <20.0 20.0-25.0 >25.0


  Optimal Borderline Increased Risk
    mg/dL  &


For more than forty years, total circulating HDL cholesterol (HDL-C) has been used as a primary indicator of cardiovascular disease (CVD) risk. However, HDL is comprised of subpopulations of different sizes, composition and characteristics that impact cardiovascular risk in drastically different ways. Data from the Framingham Heart Study, Framingham Offspring Study, Veterans Affairs HDL Cholesterol Intervention Trial (VA-HIT) and HDL-Atherosclerosis Treatment Study (HATS) have shown that HDL subpopulations are significantly better predictors of CVD risk than HDL-C values alone. The Boston Heart HDL Map® is the only test available that quantifies the amount of apoA-I in the five most significant subpopulations, resulting in a deeper understanding of a patient’s CVD risk. This exclusive method provides healthcare providers with an accurate and consistent indication of reverse cholesterol transport by separating the larger, cardioprotective particles most associated with decreased CVD risk from the smaller HDL particles associated with increased risk. Healthcare providers can use this information to determine the most effective treatment strategy, as well as monitor response to therapy.


The Boston Heart HDL Map® test measures the five most significant HDL subpopulations in CVD risk using a proprietary gel electrophoresis technique. This process quantifies the amount of apoA-I protein in each of the five HDL subclasses, providing information to accurately identify patients at increased CVD risk.

Collection Details:

Collection Instructions:

Patient Preparation: Fasting is preferred.

Preferred Specimen: 1.0 mL EDTA plasma (0.5 mL minimum) collected in plasma separator tube (Pearl Top)

Transport Temperature: Refrigerated (ship on frozen cold packs) Stability Refrigerated: 2 days (sample must be received within 2 days of collection)

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