Cancer Antigen (CA) 15-3

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Category:

Turnaround Time: Within 1 day
CPT Code: 86300
Test Type: 0.8 mL Serum
Stability Time:

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Reference Range:

0.0-25.0 units/mL

Overview:

Quantitative measurement of cancer antigen 15-3

The CA 15-3 assay value, regardless of level, should not be interpreted as absolute evidence for the presence or absence of malignant disease. The CA 15-3 assay value should be used in conjunction with information available from clinical evaluation and diagnostic procedure.

Hayes DF, Zurawski VR Jr, Kufe DW, “Comparison of Circulating CA 15-3 and Carcinoembryonic Antigen Levels in Patients With Breast Cancer,” J Clin Oncol, 1986, 4(10):1542-50. PubMed 2428949

Collection Details:

Collection Instructions:

Values obtained with different assay methods should not be used interchangeably in serial testing. It is recommended that only one assay method be used consistently to monitor each patient's course of therapy. This procedure does not provide serial monitoring; it is intended for one-time use only. If serial monitoring is required, please use the serial monitoring number 483404 to order.

This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.

Red-top tube or gel-barrier tube.

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Refrigerate.