CPT Code:


Test Type: Serum Kit Based
Stability Time:


Refrigerated: 7 days

Reference Range:
  • Low: <20 mmol/L
  • Normal: 20-31 mmol/L
  • High: >31 mmol/L
  • Alert: ≤10 or ≥40 mmol/L


Bicarbonate is an electrolyte used by the body to maintain acid/base balance. (pH). Measures the most prevalent form of total carbon dioxide in the blood which is bicarbonate.

  • Elevated levels of CO2 can indicate chronic obstructive pulmonary disease, emphysema, or pneumonia, hypertension, metabolic alkalosis.
  • Low levels can indicate cirrhosis or liver failure, diabetic ketoacidosis, metabolic or respiratory acidosis, kidney disease, or aspirin overdose.

Methodology - Enzymatic using phosphoenolpyruvate carboxylase (PEPC)

Collection Details:

Collection Instructions:

Preferred Specimen

1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST/Tiger Top)

Transport Temperature

Refrigerated (ship on frozen cold packs)