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The Comprehensive Plus Panel expands on the Comprehensive Hormone Panel and includes estrone (E1) and estriol (E3) plus the Estrogen Quotient. The Estrogen Quotient (EQ) is a simple ratio of the cancer protective E3 to the proliferative estrogens E1 and E2. The EQ provides an assessment of breast cancer risk, with a lower number (<1.0) indicating increased risk, and a higher number (>1.0) signifying a lower risk. For maximum protection, an optimal EQ is >1.5.
Because the research on the Estrogen Quotient and the protective properties of estriol has not been done with men, this panel is currently recommended for women only. This panel should be considered for patients who have:
Peforming Lab: Labrix; LABRIX; labrix
Patient Preparation:
Wash hands and rinse mouth with water to remove food residue. After rinsing mouth, wait at least 10 minutes before collecting saliva to avoid sample dilution.
Wash face before bedtime the night before collecting saliva, and do not apply lotions or creams that night or next morning (some may contain interfering substances). Use of routine cosmetics is permitted.
Do not brush, floss teeth or have dental work done 30 minutes prior to collecting saliva. Slight bleeding from these may alter test results.
The timing of the first morning collection is critical; it must be collected thirty minutes after awakening. Begin timing upon awakening even if you remain in bed.
Avoid food one hour prior to saliva collection times. Food particles will contaminate the sample.
If testing melatonin: Please avoid all nuts, fruits, fruit juice, wine, rice and coffee on the day of collection
Collection Instructions:
Use of the straws included to "funnel" saliva into each tube is optional.
Each tube should be 3/4 full - bubbles or foam are acceptable
FILL ALL FOUR TUBES regardless of how many tests are ordered.
After each collection, place the sample in the freezer immediately.
Please dispose of straws before shipping.
Freeze the samples along with the cold pack for at least 4-6 hours, or overnight if you finish the collection at night. Keep in the freezer until you are ready to ship.
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