Direct Bilirubin (1033)

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CPT Code:


Test Type: Serum Kit Based
Stability Time:


Refrigerated: 7 days

Reference Range:
  • Normal: 0.0-0.3 mg/dL
  • High: >0.3 mg/dL


Bilirubin is a protein and natural by-product of red blood cell breakdown. Measures the amount of bilirubin formed in the liver to become water-soluble.

  • If direct bilirubin is elevated more than total bilirubin, there typically is a problem with decreased elimination of bilirubin by the liver cells.
  • Elevated serum levels could indicate liver diseases such as hepatitis, cirrhosis, neoplasm or gall bladder disease.
  • Low levels are generally not a concern and are not monitored.

Methodology - Photometric

Collection Details:

Collection Instructions:

Preferred Specimen

1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST/Tiger Top)

Transport Temperature

Refrigerated (ship on frozen cold packs)