Estrogens, Total

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Category:

Turnaround Time: 2 - 4 days
CPT Code: 82672
Test Type: 0.8 mL Serum or plasma
Stability Time:

Temperature

Period

Room temperature

3 days

Refrigerated

7 days

Frozen

14 days

Freeze/thaw cycles

Stable x3
Reference Range:

See table.1

 

Age

Male (pg/mL)

Female (pg/mL)

Prepubertal

<40

<40

Adults

40−115

Female cycle:

Castrate: <40

1 to 10 d: 61−394

11 to 20 d: 122−437

21 to 30 d: 156−350

Postmenopausal: <40

HMG treatment for ovulation induction: 400−800

Tanner Stage

I

10−38

10−46

II

17−45

22−63

III

22−55

24−110

IV

27−80

40−180

V

25−80

60−280

Overview:

Evaluate for ovarian estrogen producing tumor in the premenarcheal and postmenopausal female; evaluate estrogen excess in males. Estrogen analysis may be helpful in establishing time of ovulation and optimal time for conception. Serial samples must be collected over several days to evaluate baseline and peak total estrogen levels.

1. Tietz NW, ed. Clinical Guide to Laboratory Tests. 3rd ed. Philadelphia, Pa: WB Saunders Co;1995:220.

Ashby CD, Danzer HC, Swerdloff RS, et al. Estrogen radioimmunoassay suitable for the monitoring of ovulation induction. Clin Chem. 1980; 26(8):1143-1146. PubMed 7389084

Marshall JR. Induction of ovulation. Clin Obstet Gynecol. 1978; 21(1):147-162 (review). PubMed 343954

Taymor ML, Yussman MA, Gminski D, et al. Estrogen monitoring in ovulation induction. Fertil Steril. 1970; 21(11):759-762. PubMed 5474219

Collection Details:

Patient Preparation:

Patient must avoid having radioisotope scan prior to collection of specimen.

Collection Instructions:

Red-top tube, gel-barrier tube, or green-top (heparin) tube.

If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.

Refrigerate.