Follicle Stimulating Hormone (FSH) (1122)

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Category:

CPT Code:

83001

Test Type: 1.0 mL serum Kit Based

Overview:

FSH is one of the gonadotropins of the anterior pituitary gland that stimulates the growth and maturity of graafian follicles in the ovary and spermatogenesis in the testes.

Methodology

Immunoassay – Sandwich principle

  • FSH is used to assess for dysfunctions within the hypothalamic-pituitary-gonadal system1-4
  • FSH in conjunction with LH is used for the following indications:1-4
    • Menopausal syndrome
    • Polycystic ovarian syndrome (PCOS)
    • Testosterone deficiency
    • Amenorrhea (causes)
    • Congenital diseases with chromosomal aberrations
    • High doses of biotin (> 5 mg/day) may interfere with assay results. Patient assumed to be refraining from biotin supplementation for at least 3 days prior to blood draw.

References:

  1. Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in men with androgen deficiency syndromes: Endocrine Society clinical practice guidelines. J Clin Endorcinol Metab. 2010;95(6):2536-2559.
  2. Santen RJ, Allred DC, Ardoin SP, et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab. 2010;95(7 Suppl 1):s1-s66.
  3. Kopper NW, Gudeman J, Thompson DJ. Transdermal hormone therapy in postmenopausal women: a review of the metabolic eff ects and drug delivery technologies. Drug Des Devel Ther. 2008;2:193-202.
  4. Goodman N, Cobin RH. Reproductive disorders. In: Camacho PM, Gharib H, Sizemore GW, eds. Evidence-Based Endocrinology. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins. 2012:190-22

Collection Details:

Collection Instructions:

Preferred Specimen

1.0 mL serum (0.5 mL minimum) collected in serum separator tube (SST / Tiger Top)

 

Transport Temperature

Refrigerated (ship on frozen cold packs)

Stability

Refrigerated: 14 days