Gynecologic Pap Test, Liquid-based Preparation

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CPT Code:


Test Type: ThinPrep® Pap test


Limitations: Failure to obtain adequate ectocervical, endocervical, or vaginal cell population is suboptimal for evaluation. Excessive use of lubricating jelly on the vaginal speculum will interfere with cytologic examination and may lead to unsatisfactory Pap results.

Methodology: ThinPrep® Pap test system; TriPath SurePath® Pap test

Special Instructions: Include date of birth, Social Security number (or other identification number), previous malignancy, drug therapy, radiation therapy, last menstrual period (LMP), postmenopausal patient (PMP), surgery (including surgical biopsies), exogenous hormones, abnormal vaginal bleeding, abnormal Pap results, IUD, and all other pertinent clinical information on the cytology test request form.

Note: In accordance with criteria established by CLIA, Pap tests will be referred for pathologist review if laboratory personnel suspect:

• Reactive or reparative cellular changes
• Atypical squamous or glandular cells of undetermined significance
• Cells in the premalignant or malignant category

In these cases, LabCorp will charge for the associated service. (Slides that are routinely reviewed by a pathologist for quality control purposes are not included.)


Collection Details:

Collection Instructions:

specimen: Vial with PreservCyt® solution, ThinPrep®; SurePath® vial with CytoRich™ fixative

Collection: When using the ThinPrep® method, a gynecologic specimen is collected using a brush and plastic spatula as a cervical sampling system.

Insert the brush into the endocervical canal until only the bottommost fibers are exposed. Slowly rotate the brush 1/4 to 1/2 turn in one direction. Do not over-rotate the brush. Then, rotate the brush in the PreservCyt® solution 10 times while pushing against the wall of the ThinPrep® vial. Swirl the brush vigorously to release additional material. Discard the brush. Obtain an adequate sample from the ectocervix using a plastic spatula. Swirl the spatula vigorously in the PreservCyt® vial 10 times, and discard the spatula. Tighten the cap on the ThinPrep® PreservCyt® solution container so that the torque line on the cap passes the torque line on the vial.

When using the TriPath SurePath™ method, the cervix (broom) or the endocervical brush/plastic spatula combination collection device(s) must be used with the broom/brush being inserted into the cervical os and rotated five times.

Once collected, the removable head(s) of the collection device(s) is dropped into the CytoRich™ preservative fluid in the TriPath SurePath™ collection vial. Also, the cervix brush and Wallach brush may be used in obtaining a ThinPrep® specimen, but the brush is rinsed vigorously in the vial and discarded; the brush head is not placed in the ThinPrep® PreservCyt® vial.

Record the patient's name and ID number on the vial, and place it and the test request form in a specimen bag for transport to the laboratory.