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Overview:
Determine the plasma level of unfractionated heparin (UFH) or low molecular weight heparin (LMWH)
Patient Preparation:
If the patient's hematocrit exceeds 55%, the volume of citrate in the collection tube must be adjusted. Refer to Coagulation Collection Procedures for directions. Heparin anti-Xa levels should be drawn six hours after initiation of unfractionated heparin therapy or change in dose, whereas, with low molecular weight heparin, levels should be drawn six hours after administration when given once daily and three to four hours when administered twice daily. Fondaparinux levels should be measured three hours postadministration. Therapeutic monitoring of fondaparinux should be performed using Fondaparinux Anti-Xa [500465].
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