Human T-Cell Lymphotropic Virus 1, 2 (HTLV-1/HTLV-2) Differentiation, Immunoblot

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Turnaround Time: 3 - 6 days
CPT Code:

86687, 86688

Test Type: 0.5 mL Serum or plasma


HTLV-1 infections can be confirmed and differentiated from HTLV-2 infections by using highly purified recombinant proteins or synthetic peptides which are either type common or type specific.

This test is not for screening purposes and should be used as supplementary testing for patients previously identified as reactive for antibodies to HTLV.

Sullivan MT, Williams AE, Fang CT, Grandinetti T, Poiesz BJ, Ehrlich GD. Transmission of human T-lymphotropic virus types I and II by blood transfusion. A retrospective study of recipients of blood components (1983 through 1988). The American Red Cross HTLV-I/II Collaborative Study Group. Arch Intern Med. 1991 Oct; 151(10):2043-2048. PubMed 1929693

Zrein M, Louwagie J, Boeykens H, et al. Assessment of a new immunoassay for serological confirmation and discrimination of human T-cell lymphotropic virus infections. Clin Diagn Lab Immunol. 1998 Jan; 5(1):45-49. PubMed 9455879

Collection Details:

Collection Instructions:

Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or yellow-top (ACD) tube.

Refrigerate or freeze (Pour serum or plasma into plastic pour-off tube before freezing.). Stable 2°C to 8°C for seven days or -20°C for longer storage.