Immunofixation (IFE) and Protein Electrophoresis, 24-Hour Urine

Useful in characterizing the species of protein or proteins in cases of proteinuria. Techniques can identify albumin, gamma globulin, gamma globulin fragments (light chains, Bence Jones proteins). Of value in the study of monoclonal gammopathies, lymphoproliferative diseases, including lymphoma; special application to multiple myeloma, macroglobulinemia of Waldenstrom and amyloidosis. Monoclonal gammopathy (M spike) work-up.