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Register NowLiver-Kidney Microsomal (LKM) Antibodies
Create a Free Account to View PricesTurnaround Time: 2 - 3 days
CPT Code: 86376
Test Type: 1 mL Serum
Stability Time:
|
Temperature |
Period |
|---|---|
|
Room temperature |
14 days |
|
Refrigerated |
14 days |
|
Frozen |
14 days |
|
Freeze/thaw cycles |
Stable x4 |
Reference Range:
• Negative: 0.0−20.0
• Equivocal: 20.1−24.9
• Positive: >24.9
Overview:
The detection of LKM-1 antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH-2). LKM antibodies are markers of AIH-2 which usually begins in childhood and generally affects children younger than 18 years of age. LKM antibodies are associated with a more serious progression of the disease. The disease is most common between the ages of 2 to 14 and is more frequent in females than males (8:1). LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection.
A negative LKM-1 result does not rule out the presence of autoimmune hepatitis type 2. LKM-1 may be detected in some patients as a result of HCV infection and may not be the result of AIH-2.
Collection Details:
Collection Instructions:
Red-top tube or gel-barrier tube.
To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Room temperature.