Metabolic Syndrome / Insulin Resistance Syndrome Profile

Identify individuals with metabolic syndrome. The National Cholesterol Education Program, Adult Treatment Panel III guidelines indicate that metabolic syndrome is present in patients with any three of the following five symptoms:

- HDL <40 mg/dL in men and <50 mg/dL in women

- Triglycerides ≥150 mg/dL

- Glucose ≥110 mg/dL

- Blood pressure ≥130/85

- Waist circumference >40” in men and >35” in women

Metabolic syndrome conveys an increased risk of diabetes, hypertension, gallbladder disease, osteoarthritis, and cardiovascular disease.

This profile should not be performed on patients who have, in the preceding three months, suffered a myocardial infarction or similar traumatic episode, including acute infection or inflammation.

Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2003 Jan 1; 289(1):76-79. PubMed 12503980

National Heart, Lung, and Blood Institute. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Bethesda, Md: National Heart, Lung, and Blood Institute, National Institutes of Health; 2001. NIH Publication 02-5215.