MycoTOX Profile - Urine

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Category:

Turnaround Time: 1 - 2 weeks
Test Type: Kit Based, Urine
Stability Time:

7 days refrigerated and 6 months frozen

Overview:

Mycotoxins, produced by certain mold species, are some of the most prevalent toxins and can come from many sources, including buildings, vehicles, and food. These compounds have been recognized as a growing global health concern due to their acute and chronic adverse health impacts. Mycotoxin exposure can be challenging to diagnose without proper testing due to vague and often varied symptoms. The MycoTOX Profile? is Mosaic Diagnostics? most comprehensive assessment of mycotoxins. Our state-of-the-art urine-based assay accurately assesses levels of 11 different mycotoxins, including Aflatoxin M1, Ochratoxin A, Zearalenone, and Trichothecenes. The MycoTOX Profile? has been designed to help clinicians uncover mycotoxin exposure and guide a therapeutic strategy for prevention and treatment. Why Test for Mycotoxins? Mycotoxins cause adverse health effects that may be acute and chronic in nature that can manifest in various and ambiguous symptoms, the degree of impact can vary depending on the age, sex, genetics, and underlying health status of the exposed individual, as well as the duration and dose magnitude of the offending substance and their synergistic effects with other mycotoxins. Providers assessing symptomatic patients with known mold exposure or with an environmental history concerning mold exposure, will also need to consider the concomitant presence of mycotoxins and their potential negative health impacts as proper testing is essential for accurate treatment. The MycoTOX Profile? is specifically designed to help healthcare practitioners identify mycotoxin exposure and guide a targeted prevention and treatment plan. How Can Someone Be Exposed to Mycotoxins? Common routes of exposure include inhalation, dermal contact, and ingestion via commonly contaminated food sources (corn, cereals, ground and tree nuts, spices, dried fruits, apples, coffee, meat, milk, and eggs). Mold contamination can also affect nearly all indoor materials, including drywall, paint, wallpaper, carpeting, and more, posing various routes of exposure. When excessive moisture is present in high-humidity geographic areas or water-damaged buildings, the growth of these biological agents in damp environments leads to the production of spores, cells, fragments, and volatile organic compounds, which have been linked to a wide range of health hazards. How Does the MycoTOX Profile Measure Mycotoxins? The MycoTOX Profile? utilizes state-of-the-art liquid chromatography tandem mass spectrometry (LC-MS/MS) technology to ensure high specificity (or fewer false positive results) and capture free (unconjugated) mycotoxin presence even at low levels. This is crucial, as mycotoxins, even at low levels of exposure, can cause serious health problems. Our test is so sensitive that we can detect amounts of many compounds in parts per trillion (ppt). To account for variations in fluid intake, we utilize creatinine correction to ensure accurate and reliable results. By employing LC-MS/MS technology, we can precisely identify all our analytes, reducing the risk of false positives. With the MycoTOX Profile?, you can trust that you are receiving the most accurate and reliable results possible.

Collection Details:

Patient Preparation:

Avoid the following for at least three days prior to collecting:Glutathione, Bentonite Clay or similar binders, Charcoal If taking Mycophenolate mofetil (CellCept/Myfortic), be sure to consult with your physician on when or if you can abstain from taking this medication for 72 hours prior to sample collection.

Collection Instructions:

Preparing For Your Test ? Plan now to collect your sample first thing in the morning, and early in the week. For US collections, collect your ?first morning sample? on a Monday-Thursday morning. Outside the US, the sample should be collected on Monday or Tuesday to allow extra time for shipping. ? Collect your first urine specimen in the morning before eating or drinking. This is the most concentrated collection. ? Avoid contamination of samples with blood or while menstruating as this may interfere with test results. Wait until the following week. ? Place the Collection Cup and these instructions in the bathroom where you plan to collect the samples in the morning. Set the rest of the contents aside. ? Place the ice pack flat in your freezer, so it will be ready to ship with your specimen. ? Pediatric collection bags are available upon request for children not potty trained to aid with collection. Collection Day Instructions: ?Look at the volume markings on the side of the collection cup. You will need a minimum of 10 mL for each test on the order. ?Verify how many tests have been ordered, so you know how much sample to collect. ?Collect your first morning urine sample in the provided collection cup. DO NOT eat or drink prior to collecting your sample. Please collect at least the minimum amount of urine required for the number. of tests on your order. Collecting more than the minimum is recommended, but not required. Pour off anything above 50 mL indicator line to prevent leaking once frozen. ?Locate and complete the barcode sheet in your test kit. Place one barcode sticker on each collection sample. Be sure that the information is legible and includes the collection date, time, and that the name matches what was provided on the test order. After You Collect: ? Fill any other vials that have been included for other urine tests. Follow the instructions in those test kits for collections.? Place the lid on the collection cup and seal tightly. ? Ensure each sample has the completed barcode sticker. ? Place the collection cup in your freezer for at least four hours or until frozen (30 days maximum). Check the box on the barcode label to indicate that the sample has been frozen. ? Ensure all samples are labeled. Unlabeled samples will be rejected. Packaging the shipment: ?Retrieve the packaging material you set aside. Locate the clear biohazard zip-lock bag, silver thermo bag, and absorbent packing sheet. ?Remove the frozen collection cup, frozen ice pack, and any vials for other urine tests from the freezer and check caps for tightness. ?Place all frozen specimens and absorbent packing sheet in the biohazard zip-lock bag and seal. ?Place the sealed biohazard zip-lock bag into the silver thermo bag along with the frozen ice pack. ?Place the filled silver thermo bag into the box. If using the Test Requisition Form, also place in box. Close the lid. Locate the shipping instruction card included in your test kit for details on how to ship your collection(s)