Myeloperoxidase (MPO)

Elevated levels of plasma MPO are a sensitive indicator of inflammatory disorders.

Erratic results can be observed if plasma is not centrifuged and separated from red cells immediately.

Results of this test are labeled for "research purposes only." The result should not be used for treatment or for diagnostic purposes without confirmation of the diagnosis by another medically established diagnostic product or procedure. The performance characteristics were determined by LabCorp.

MPO plays an important role in the innate host-defense mechanism of human and animals.

Myeloperoxidate (MPO) is a hemoprotein present in leukocytes and catalyzes the hydrogen peroxide mediated peroxidation of halide ions to produce strong reactive oxidant species such as hypochlorous acid that are of potent antimicrobial activities against a broad range of invading parasites and pathogens. However, MPO-derived reactive oxidants also promote host tissue injury through lipid and protein peroxidations that lead to systemic inflammation.

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