Natural Killer Cell Surface Antigen (CD3-CD56+ Marker Analysis)

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Turnaround Time: 1 - 3 days
CPT Code:


Test Type: Whole blood, fill tube(s) to capacity


Determine levels of natural killer cells in circulation; monitor immune stimulation therapy.

Natural killer (NK) cells are large granular lymphocytes that mediate MHC-unrestricted cytotoxicity against virus-infected and malignant cells and manufacture a number of cytokines following stimulation of the immune system.

Centers for Disease Control and Prevention (CDC). 1997 revised guidelines for performing CD4+ T-cell determinations in persons infected with human immunodeficiency virus (HIV).MMWR. 1997 Jan 10; 46:RR-2.

Collection Details:

Collection Instructions:

Lavender-top (EDTA) tube and yellow-top (ACD-A) or (ACD-B) tube.

Invert tube 8 to 10 times immediately after collection. To preserve cellular viability, collect specimen so it will arrive in the laboratory within 48 hours of collection. Indicate date and time of venipuncture on the tube(s) and on the test request form.

Maintain specimen at room temperature.