Single Lab Test

Nicotine and Metabolite, Quantitative, Plasma, Whole Blood, or Serum

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Categories
Basic Laboratory Assessment
:
Screening
Turnaround Time
3 - 7 days
CPT Code
80323
Test Type

1 mL Plasma, whole blood, or serum

Overview

Measurement of nicotine and its metabolites to monitor success of smoking cessation programs, detect passive exposure, and evaluate nontobacco nicotine exposure.

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

Analytical Validation Report. Quantification of Nicotine and Metabolites by LC-MS/MS Analysis. Unpublished LabCorp Internal Document Number VR-NOQS-BN-2008-06.

James G, et al. A Highly Sensitive Method for the Quantitation of Nicotine, Cotinine, and Trans-3'-Hydroxycotinine in Human Plasma (EDTA). ASMS Poster 1014, 2007.

Moyer TP, Charlson JR, Enger RJ, et al. Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles. Clin Chem. 2002 Sep; 48(9):1460-1471. PubMed 12194923

Xu X, Iba MM, Weisel CP. Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry. Clin Chem. 2004 Dec; 50(12):2323-2330. PubMed 15472033

Collection Details

Patient Preparation:

Collection Instructions:

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