Parathyroid Hormone (PTH) (1136)

PTH is a hormone secreted by the parathyroid glands that is important in bone remodeling. PTH functions as part of a feedback system that involves calcium, phosphorus (as phosphate), and vitamin D.

Methodology

Electrochemiluminescence Immunoassay (ECLIA)

• Used to help diagnose the cause of a low or high calcium level and to help distinguish between parathyroid-related and non-parathyroid-related causes.
• A calcium test is almost always ordered along with PTH to determine the balance between calcium and PTH and the response of the parathyroid glands to changing levels of calcium.
• Most often ordered when calcium regulation is abnormal.
• High doses of biotin (> 5 mg/day) may interfere with assay results. Patient assumed to be refraining from biotin supplementation for at least 3 days prior to blood draw.