PMP22 MLPA Deletion/Duplication Analysis

Use: Mutations in the PMP22 gene cause several forms of a neurological disorder called Charot-Marie-Tooth disease. This disorder damages the peripheral nerves, which can result in loss of sensation and wasting (atrophy) of muscles in the feet, legs and hands.

Limitations: This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

Methodology: Multiplex Ligation-dependent Probe Amplification