Systemic Lupus Erythematosus (SLE) Profile C

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Turnaround Time: Within 1 day
CPT Code:

86225, 86235(4)

Test Type: 1 mL Serum
Stability Time:

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Reference Range:

RNP Antibodies AI 0.0 – 0.9
Smith antibodies AI 0.0 – 0.9
Sjogren’s anti-SS-A AI 0.0 – 0.9
Sjogren’s Anti-SS-B AI 0.0 – 0.9
Anti-DNA Ab Qn IU/mL 0 - 9

Overview:

Sensitive assay for screening for ANAs in patients suspected of having SLE.

Low antibody levels may be found in diseases other than connective tissue disease.

Kopnitsky M, Meenan J. AtheNA Multilyte ANA test system: The next generation of antinuclear testing. Clin Lab Products. 2002; 31:38-49.

Tan EM, Chan EK, Sullivan KF, et al. Antinuclear antibodies (ANAs): Diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity. Clin Immunol Immunopathol. 1988; 47(2):121-141. PubMed 3280190

von Mühlen CA, Nakamura RM. Clinical and laboratory evaluation of systemic rheumatic diseases. In: Henry JB, ed. Clinical Diagnosis and Management by Laboratory Methods. 20th ed. Philadelphia, Pa: WB Saunders Co; 2001: 974-989.

von Mühlen CA, Tan EM. Autoantibodies in the diagnosis of systemic rheumatic diseases. Semin Arthritis Rheum. 1995 Apr; 24(5):323-358. PubMed 7604300

Collection Details:

Collection Instructions:

Red-top tube or gel-barrier tube.

Maintain specimen at room temperature.