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Overview:
Patient Preparation:
Ideally the patient should not be on anticoagulant therapy. Avoid warfarin (Coumadin®) therapy for two weeks prior to the test and heparin, direct Xa and thrombin inhibitor therapies for about three days prior to testing.
Collection Instructions:
• If PT is abnormal (above normal reference interval), the test will reflex to PT mixing studies and factor VII activity.
• If aPTT is abnormal (above normal reference interval), the test will reflex to aPTT mixing studies, hexagonal phospholipid neutralization, factor XI activity, factor IX activity, and factor VIII activity.
• If TT is abnormal (above normal reference interval), the test will reflex to fibrinogen activity and fibrinogen antigen.
• If reflex testing is performed, concomitant CPT codes/charges will apply.
Blue-top (sodium citrated) tubes.
Plasma must be separated from cells within 45 minutes of venipuncture and centrifuged a second time before being placed in plastic transport tubes. Freeze within two hours and keep frozen until testing is performed. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Freeze.
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