Bartonella Antibody Profile

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Turnaround Time: 1 - 5 days
CPT Code:

86611(x4)

Test Type: 2 mL Serum

Overview:

Bartonella (formerly Rochalimaea) henselae has become firmly established as the primary etiologic agent for cat scratch disease (CSD). Bartonella quintana, known for some time as a cause of trench fever, is also associated with CSD and bacillary angiomatosis (BA). Both diseases frequently affect immunocompromised patients, particularly those infected with HIV-1. Although CSD is generally a self-limiting disease, it can be life-threatening.

There is some cross-reactivity between the IgG classes of B henselae and B quintana.

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA). The FDA has determined that such clearance or approval is not necessary.

Anderson BE, Neuman MA. Bartonella spp as emerging human pathogens. Clin Microbiol Rev. 1997 Apr; 10(2):203-219. PubMed 9105751

Chomel BB, Abbott RC, Kasten RW, et al. Bartonella henselae prevalence in domestic cats in California: Risk factors and association between bacteremia and antibody titers. J Clin Microbiol. 1995 Sep; 33(9):2445-2450. PubMed 7494043

Regnery RL, Anderson BE, Clarridge JE 3rd, Rodríguez-Barradas MC, Jones DC, Carr JH. Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. J Clin Microbiol. 1992 Feb; 30(2):265-274. PubMed 1371515

Regnery R, Tappero J. Unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes. Emerg Infect Dis. 1995 Jan-Mar; 1(1):16-21. PubMed 8903149

Sander A, Posselt M, Oberle K, Bredt W. Seroprevalence of antibodies to Bartonella henselae in patients with cat scratch disease and in healthy controls: Evaluation and comparison of two commercial serological tests. Clin Diagn Lab Immunol. 1998 Jul; 5(4):486-490. PubMed 9665953

Welch DF, Pickett DA, Slater LN, Steigerwalt AG, Brenner DJ. Rochalimaea sp. nov., a cause of septicemia, bacillary angiomatosis, and parenchymal bacillary peliosis. J Clin Microbiol. 1992 Feb; 30(2):275-280. PubMed 1537892

Collection Details:

Collection Instructions:

Red-top tube or gel-barrier tube.

Refrigerate.