Calcium:Creatinine Ratio

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Turnaround Time: Within 1 day
CPT Code:

82340; 82570

Test Type: Urine (random)
Stability Time:

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

7 days

Freeze/thaw cycles

Stable x3

Overview:

A random urine calcium:creatinine ratio is used to screen for hypercalciuria, as it is found to have a good correlation with 24-hour urine calcium excretion.1 Increased urinary excretion of calcium accompanies hyperparathyroidism, vitamin D intoxication, diseases that destroy bone (such as multiple myeloma), metastasis from prostatic cancer, and following calcium supplementation. Urine calcium is increased with immobilization, with steroid therapy, with Paget disease, and in primary (idiopathic) hypercalciuria.

1. Longman C. Disorders of phosphorus, calcium, and vitamin D. In: Holliday MA, Barrat TM, Avner ED, eds. Pediatric Nephrology. 3rd ed. Baltimore, Md: Williams & Wilkins;1994:619-620.

Collection Details:

Collection Instructions:

Use random transport tube or urine Monovette® with pH stabilizer (Labcorp N° 56015). Monovette® instructions accompany units.

Collect urine and transfer to a random urine transport tube or urine Monovette® with pH stabilizer (LabCorp N° 56015). Final pH must be <2. After collection, pH is adjusted to 1.5-2.0 with 6N HCl.

Refrigerate.