Evexia Complete Abnormal Bleeding Profile

Overview:

The Evexia Diagnostics Complete Abnormal Bleeding Profile builds significantly from the Basic Abnormal Bleeding option.  It provides a very robust look at numerous aspects of what could cause this clinical concern.  This profile contains Clotting Factors I, VII, VIII, IX and XI, fibrinogen activity, hexagonal phase phospholipid, prothrombin time, partial thromboplastin time, and PT mixed studies.

 

Fibrinogen is an acute-phase reactant and can often become significantly increased in conditions involving tissue damage, infection, or inflammation.  Fibrinogen activity and fibrinogen antigen are used in the diagnosis of homozygous and heterozygous fibrinogen deficiency, dysfibrinogenemia, as well as the diagnosis of disseminated intravascular coagulation.  Fibrinogen levels can also be used to assess the effectiveness of thrombolytic therapy.

 

The hexagonal phase phospholipid test system is designed for the qualitative detection of lupus anticoagulants in plasma.

 

Factor VII is used to evaluate an isolated prolonged PT and document factor VII deficiency.

 

Factor VIII is used in the evaluation of an isolated prolonged aPTT, for the diagnosis of hemophilia A, and as an aid in the diagnosis of von Willebrand factor (vWF) deficiency.

 

Factor IX is used to evaluate an isolated prolonged aPTT and to document specific factor IX deficiency.

 

Factor XI is used to evaluate isolated aPTT prolongation and to document specific factor deficiency.